Gutkowski K et al. Hepatotoxicity of drugs - causative mechanisms. Gastroenterological Review 2008; 3 (6): 271–275. MP Drug Index - description of the substance paracetamol. http://indeks.mp.pl/leki/desc.php?id=631 - DOA: 16/11/2016. Damjanov I. Diseases of the liver and biliary tract. In: Pathophysiology. Issue 1. Elsevier Urban & Partner. Wroclaw 2010: 273–278. American Liver Foundation, A Healthy Diet, a Healthier Liver, a Healthier You https://liverfoundation.org/for-patients/about-the-liver/health-wellness/nutrition/ - access date: 29/03/2021. Mokrowiecka A. The liver and fat-soluble vitamins. http://gastrologia.mp.pl/lista/64073 , liver-and-vitamins-fat-soluble. - DOA: 2016.10.16. Bojarowicz H et al. The effect of vitamin A on the condition of the skin. Probl Hig Epidemiol 2010; 91 (3): 352–356. Wolańska D. Glucose-fructose syrup and its influence on health http://dieta.mp.pl/zasady/118347 , glucose-fructose-syrup-and-his-health-impact. –DOA: 2016.10.16. Mokrowiecka A. Liver transplant. Gastrology - Practical Medicine; https://www.mp.pl/pacjent/gastrologia/choroby/watroba/74668 , transplant-watarzenia DOA: 2016.10.16 accessed on 09.05.2021 Perumpail, BJ, Khan, MA, Yoo, ER, Cholankeril, G., Kim, D., & Ahmed, A. (2017). Clinical epidemiology and disease burden of nonalcoholic fatty liver disease. World Journal of Gastroenterology, 23 (47), 8263-8276 Blachier M et al. The burden of liver disease in Europe: A review of available epidemiological data. J Hepatol 2013; 58: 593–608. Jaczewska-Schuetz J. Nutrition in liver diseases. http://dieta.mp.pl/diety/diety_w_chorobach/72098,zywanie-w-chorobach-watrawy . - DOA: 2016.10.15. Kargulewicz A et al. Nonalcoholic fatty liver disease - Etiopathogenesis, epidemiology, treatment. Nowiny Lekarskie 2010; 79: 410–418. Olszanecka-Glinianowicz M. Dukan's diet. http://dieta.mp.pl/diety/diety_alternacyjne/66570,dieta-dukana . - DOA: 2016.10.16 Morisco F. et al. Coffee and liver health; J Clin Gastroenterol 2014; 48: S87 – S90 https://journals.lww.com/jcge/Fulltext/2014/11001/Coffee_and_Liver_Health.24.aspx accessed on May 9, 2021 Jarosz M. KAWA - a rising star of disease prevention? Food and Nutrition Institute; September 2018.http : //www.izz.waw.pl/attachments/article/633/KAWA_NEWSLETTER__IZ%CC%87Z%CC%87.pdf accessed on May 9, 2021 European Society of Medical Oncology; Liver cancer: a guide for patients - Information based on ESMO Clinical Practice Guidelines - v. 2014.1; https://www.esmo.org/content/download/102688/1814031/file/PL-Rak-Wa%CC%A8troby-Poradnik-dla-Pacjento%CC%81w.pdf accessed on 09.05.2021 Juszczyk J, Pawłowska M. Acute viral hepatitis (viral hepatitis). http://gastrologia.mp.pl/choroby/watroba/50949,ostre-wirusowe-zaprzenie-watarzenia-wzw . - DOA: 2016.10.16 CDC Viral hepatitis https://www.cdc.gov/hepatitis/hcv/hcvfaq.htm#b1 access on 09/05/2021 Kozłowska-Wojciechowska M. Essential phospholipids; Therapy - in the family doctor's office, June 2014 https://terapia.com.pl/publ/id , 137491, ed, 267 accessed on 09/05/2021 Gietka J. Klapaczyński J., Fatty liver disease - diagnosis and treatment, https://podyawodie.pl/medycyna/23439,stluszczenie-watrawy-diagnostyka-i-leczenie , accessed on 29/03/2019.

A woman sits on the floor next to her dog.

How does the liver regenerate?

> What are the threats to your liver?

> How rapidly does the liver regenerate?

> How can be support hepatic regeneration?

The liver is an exceptional organ that has the ability to auto-regenerate. ¹ In contrast to other organs which – like the skin – simply replace the damaged tissue with a scar, the liver is able to rebuild the damaged or missing tissue fragments, replacing them with new cells. ¹ This process is possible owing to the presence of stem cells in the liver, from which new liver cells (hepatocytes) can be formed. ²

THE LIVER IS AN EXCEPTIONAL ORGAN THAT HAS THE ABILITY TO AUTO-REGENERATE.

What are the threats to your liver?

The main factors that may lead to liver injury are related to an unhealthy lifestyle. They include:^3,4

Excessive alcohol consumption

Unbalanced and fatty diet

Exposure to toxins and chemicals, e.g. mushroom poisoning

Frequent use of medicines (e.g. painkillers)

Certain diseases, such as viral hepatitis.

How rapidly does the liver regenerate?

The liver is able to regenerate after its toxic, infectious and surgical injury. Its regeneration ability is absolutely exceptional. It has been demonstrated that after resection of 70% of the hepatic parenchyma the human body needs only a few weeks to restore the full function of this organ. ¹

AFTER DRUG OVERDOSE

The liver needs even around 30 days to recover. Interestingly, the liver can regenerate up to 50% of its original mass. ¹

AFTER ALCOHOL CONSUMPTION

The liver needs around an hour to break down one glass of wine, 250 ml of beer or 25 ml of strong liquor.

How can be support hepatic regeneration?

As we already know, the liver has extraordinary regeneration abilities. But this process is only possible when we support it by a healthy lifestyle. Here are some tips on how to maintain a healthy liver:

Diet

The liver likes easily digestible meals and meals that contain very small amounts of fat; it is advisable to eat regularly and exclude from the diet a few foods that can have a negative effect on the liver in the long run. ⁵

Physical activity

Even the smallest amount of exercise, when practised daily, reduces the risk of obesity, diabetes or metabolic syndrome, which ones may lead in the future to a much more serious disease, which is non-alcoholic fatty liver disease (NAFLD).⁶

Taking essential phospholipids

Essential phospholipids are organic compounds that penetrate into injured hepatocytes, accelerating their regeneration.⁷

Start caring for your liver today with Essentiale

Choose the right pack size to fit your needs and find about the differences between Phospholipids (Essentiale Forte P). 50s and Phospholipids (Essentiale Forte P). 10s

Phospholipids (Essentiale Forte P) 10s

CLINICAL PARTICULARS
Indications
Nutritional support in the management of damaged liver (due to chronic liver disease, liver cirrhosis, fatty liver & intoxication by hepatotoxic substances). Each hard gelatin capsule contains: De-oiled enriched phospholipids from soya-beans …………… 300 mg

Gutkowski K et al. Hepatotoxicity of drugs - causative mechanisms. Gastroenterological Review 2008; 3 (6): 271–275.
MP Drug Index - description of the substance paracetamol. http://indeks.mp.pl/leki/desc.php?id=631 - DOA: 16/11/2016.
Damjanov I. Diseases of the liver and biliary tract. In: Pathophysiology. Issue 1. Elsevier Urban & Partner. Wroclaw 2010: 273–278.
American Liver Foundation, A Healthy Diet, a Healthier Liver, a Healthier You https://liverfoundation.org/for-patients/about-the-liver/health-wellness/nutrition/ - access date: 29/03/2021.
Mokrowiecka A. The liver and fat-soluble vitamins. http://gastrologia.mp.pl/lista/64073 , liver-and-vitamins-fat-soluble. - DOA: 2016.10.16.
Bojarowicz H et al. The effect of vitamin A on the condition of the skin. Probl Hig Epidemiol 2010; 91 (3): 352–356.
Wolańska D. Glucose-fructose syrup and its influence on health http://dieta.mp.pl/zasady/118347 , glucose-fructose-syrup-and-his-health-impact. –DOA: 2016.10.16.
Mokrowiecka A. Liver transplant. Gastrology - Practical Medicine; https://www.mp.pl/pacjent/gastrologia/choroby/watroba/74668 , transplant-watarzenia DOA: 2016.10.16 accessed on 09.05.2021
Perumpail, BJ, Khan, MA, Yoo, ER, Cholankeril, G., Kim, D., & Ahmed, A. (2017). Clinical epidemiology and disease burden of nonalcoholic fatty liver disease. World Journal of Gastroenterology, 23 (47), 8263-8276
Blachier M et al. The burden of liver disease in Europe: A review of available epidemiological data. J Hepatol 2013; 58: 593–608.
Jaczewska-Schuetz J. Nutrition in liver diseases. http://dieta.mp.pl/diety/diety_w_chorobach/72098,zywanie-w-chorobach-watrawy . - DOA: 2016.10.15.
Kargulewicz A et al. Nonalcoholic fatty liver disease - Etiopathogenesis, epidemiology, treatment. Nowiny Lekarskie 2010; 79: 410–418.
Olszanecka-Glinianowicz M. Dukan's diet. http://dieta.mp.pl/diety/diety_alternacyjne/66570,dieta-dukana . - DOA: 2016.10.16
Morisco F. et al. Coffee and liver health; J Clin Gastroenterol 2014; 48: S87 – S90 https://journals.lww.com/jcge/Fulltext/2014/11001/Coffee_and_Liver_Health.24.aspx accessed on May 9, 2021
Jarosz M. KAWA - a rising star of disease prevention? Food and Nutrition Institute; September 2018.http : //www.izz.waw.pl/attachments/article/633/KAWA_NEWSLETTER__IZ%CC%87Z%CC%87.pdf accessed on May 9, 2021
European Society of Medical Oncology; Liver cancer: a guide for patients - Information based on ESMO Clinical Practice Guidelines - v. 2014.1; https://www.esmo.org/content/download/102688/1814031/file/PL-Rak-Wa%CC%A8troby-Poradnik-dla-Pacjento%CC%81w.pdf accessed on 09.05.2021
Juszczyk J, Pawłowska M. Acute viral hepatitis (viral hepatitis). http://gastrologia.mp.pl/choroby/watroba/50949,ostre-wirusowe-zaprzenie-watarzenia-wzw . - DOA: 2016.10.16
CDC Viral hepatitis https://www.cdc.gov/hepatitis/hcv/hcvfaq.htm#b1 access on 09/05/2021
Kozłowska-Wojciechowska M. Essential phospholipids; Therapy - in the family doctor's office, June 2014 https://terapia.com.pl/publ/id , 137491, ed, 267 accessed on 09/05/2021
Gietka J. Klapaczyński J., Fatty liver disease - diagnosis and treatment, https://podyawodie.pl/medycyna/23439,stluszczenie-watrawy-diagnostyka-i-leczenie , accessed on 29/03/2019.