Is it true that some drugs can be dangerous for the liver?

Yes it is true. A vast majority of drugs are metabolized in the liver, which in some cases can lead to damage to liver cells (hepatocytes). In this case, we are talking about drug damage to the liver.(1) Taking overdoses or multiple drugs that can interact can be dangerous for the liver. One of the commonly used drugs with potentially hepatotoxic effect is paracetamol. It is available in single-ingredient drugs and in many medicine so there is a high risk of overdose. It should be borne in mind that the maximum allowable daily dose of this active substance (contained in painkillers and cold medicines) is 4,000 mg for adults. Symptoms of liver damage may occur by taking only twice the maximum recommended daily dose. More information on the effects of drugs on the liver is available here.(2)

Is it true that fried foods are a burden on the liver?

Yes it is true. A diet suitable for the liver should be easily digested, with limited amounts of fats, sugars and salt. Fried foods and fast foods should be avoided. The diet should be balanced and should include foods of all groups: cereals, vegetables, fruits, dairy products, meat and oils. It is very important to drink water and reduce alcohol consumption.(4) However, it should be borne in mind that the diet of people with liver problem should be selected individually, taking into account the nutritional status of the patient and the needs of his body.

Is it true that excessive amounts of sugar in the diet have a negative effect on the liver?

Yes it is true. Glucose-fructose syrup, which is commonly added to beverages and other processed food products, is actually very harmful to the liver. That syrup contains a large amount of fructose, which is 99% absorbed by the liver and stimulates this organ to produce adipose tissue. Studies suggest that high fructose intake may increase the risk of excess fat accumulation in liver cell. (7)

Is it true that the liver does not feel hurt?

Yes it is true. The liver does not contain nerve, so it does not cause pain. However, due to many different problems, the liver may enlarge and the fibrous sheath may be compressed on the surface of the liver, the so-called Glisson's sheath. Glisson’s capsule has sensory innervation, which is why its tension may cause a sensation of pressure or even pain. (3)

Is it true that an excessive amount of vitamin A is not suitable for the liver?

Yes it is true. Vitamin A is metabolized and stored in the liver. Its use in high doses can be toxic and lead to hypervitaminosis (excess vitamin in the body), a condition that is dangerous for the liver. (5,6) Accumulation of vitamin A in the liver can even lead to liver problem. Therefore, always follow the recommended dosage when using dietary supplements. It is also important to make sure that you do not take several supplements with a similar composition. (5,6)

Is it true that the liver is neutralized by harmful substances?

Yes, but this is far from the only role of the liver. The liver is truly a high-performance "factory," performing many vital functions on a daily basis.

Is liver problems caused by fat accumulation in liver cells common?

Yes, you can say that it is common. It is estimated that 1 in 4 adult can be affected by this condition. An estimated one billion people worldwide live with the condition! (8)

Is it enough to take medication and supplements to take good care of your liver?

Primarily, it is necessary to change eating habits - it is necessary to avoid fats of animal origin, limit the intake of simple sugars (i.e. confectionery), completely eliminate sugary drinks, it is also recommended to avoid spicy spices and easy to cause gas foods (e.g. cabbage, onions, legumes, asparagus, plums, pears, cherries).(11) It is good to start with regular physical activity, which facilitates weight loss.(12)

Is weight loss for overweight or obese people always beneficial for the liver?

Weight loss is beneficial for liver function, but only if it is not too drastic or too quick. Weight reduction of 10% in 3 to 6 months brings an improvement in health - but it must be achieved according to a suitable schedule, i.e. about 1 kg per week. (13) Drastic diets leading to rapid weight loss usually do not have a lasting effect and can cause rapid release of large amounts of fats and toxins into the bloodstream, leading to fat accumulation in liver. The so-called monotrophic diet is not suitable for the liver either, where nutrients from almost exclusively one product group are delivered to the body. An example is the popular Dukan diet (i.e. low carb diet), in which excessive protein consumption has a negative effect on liver health.(13)

Is drinking coffee harmful to the liver?

It is time to put this myth to justice. Studies show the multiple health benefits of drinking coffee. Coffee has been shown to have a positive effect on liver enzymes, fat accumulation in liver. (14,15) But there are a few rules to follow when drinking coffee. Ask your health care professional if your have any questions on it.

Is it true that fat accumulation in liver only affects obese people?

No. it is not true. Fat accumulation in liver is the most common liver problem in developed countries. In addition, its incidence is still increasing, which is related to the increasing incidence of obesity. Research studies show that this problem affects 70% of obese people. (16)

FACTS AND MYTHS ABOUT THE LIVER

We present the facts and dispel the myths about the liver and its functions.

FACTS

Yes it is true. A vast majority of drugs are metabolized in the liver, which in some cases can lead to damage to liver cells (hepatocytes). In this case, we are talking about drug damage to the liver.⁽¹⁾ Taking overdoses or multiple drugs that can interact can be dangerous for the liver. One of the commonly used drugs with potentially hepatotoxic effect is paracetamol. It is available in single-ingredient drugs and in many medicine so there is a high risk of overdose. It should be borne in mind that the maximum allowable daily dose of this active substance (contained in painkillers and cold medicines) is 4,000 mg for adults. Symptoms of liver damage may occur by taking only twice the maximum recommended daily dose. More information on the effects of drugs on the liver is available here.⁽²⁾
Yes it is true. A diet suitable for the liver should be easily digested, with limited amounts of fats, sugars and salt. Fried foods and fast foods should be avoided. The diet should be balanced and should include foods of all groups: cereals, vegetables, fruits, dairy products, meat and oils. It is very important to drink water and reduce alcohol consumption.⁽⁴⁾

However, it should be borne in mind that the diet of people with liver problem should be selected individually, taking into account the nutritional status of the patient and the needs of his body.
Yes it is true. Glucose-fructose syrup, which is commonly added to beverages and other processed food products, is actually very harmful to the liver. That syrup contains a large amount of fructose, which is 99% absorbed by the liver and stimulates this organ to produce adipose tissue. Studies suggest that high fructose intake may increase the risk of excess fat accumulation in liver cell. ⁽⁷⁾
Yes it is true. The liver does not contain nerve, so it does not cause pain. However, due to many different problems, the liver may enlarge and the fibrous sheath may be compressed on the surface of the liver, the so-called Glisson's sheath. Glisson’s capsule has sensory innervation, which is why its tension may cause a sensation of pressure or even pain. ⁽³⁾
Yes it is true. Vitamin A is metabolized and stored in the liver. Its use in high doses can be toxic and lead to hypervitaminosis (excess vitamin in the body), a condition that is dangerous for the liver. ^(5,6) Accumulation of vitamin A in the liver can even lead to liver problem. Therefore, always follow the recommended dosage when using dietary supplements. It is also important to make sure that you do not take several supplements with a similar composition. ^(5,6)
Yes, but this is far from the only role of the liver. The liver is truly a high-performance "factory," performing many vital functions on a daily basis.
Yes, you can say that it is common. It is estimated that 1 in 4 adult can be affected by this condition. An estimated one billion people worldwide live with the condition! ⁽⁸⁾

MYTHS

Primarily, it is necessary to change eating habits - it is necessary to avoid fats of animal origin, limit the intake of simple sugars (i.e. confectionery), completely eliminate sugary drinks, it is also recommended to avoid spicy spices and easy to cause gas foods (e.g. cabbage, onions, legumes, asparagus, plums, pears, cherries).⁽¹¹⁾ It is good to start with regular physical activity, which facilitates weight loss.⁽¹²⁾
Weight loss is beneficial for liver function, but only if it is not too drastic or too quick. Weight reduction of 10% in 3 to 6 months brings an improvement in health - but it must be achieved according to a suitable schedule, i.e. about 1 kg per week. ⁽¹³⁾

Drastic diets leading to rapid weight loss usually do not have a lasting effect and can cause rapid release of large amounts of fats and toxins into the bloodstream, leading to fat accumulation in liver. The so-called monotrophic diet is not suitable for the liver either, where nutrients from almost exclusively one product group are delivered to the body. An example is the popular Dukan diet (i.e. low carb diet), in which excessive protein consumption has a negative effect on liver health.⁽¹³⁾
It is time to put this myth to justice. Studies show the multiple health benefits of drinking coffee. Coffee has been shown to have a positive effect on liver enzymes, fat accumulation in liver. ^(14,15) But there are a few rules to follow when drinking coffee. Ask your health care professional if your have any questions on it.
No. it is not true. Fat accumulation in liver is the most common liver problem in developed countries. In addition, its incidence is still increasing, which is related to the increasing incidence of obesity. Research studies show that this problem affects 70% of obese people. ⁽¹⁶⁾

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